Recent disclosures of clinical candidates: Highlights from the Society of Medicines Research Symposium. The National Heart and Lung Institute, London, U.K. - December 1, 2016

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摘要
This symposium featured an international lineup of speakers presenting on the discovery and clinical development of novel therapeutic agents. The presentations described a variety of mechanistic approaches including small molecules, monoclonal antibodies and a drug repurposing and covered therapeutics areas from oncology, anti-infectives and inflammation to anemia. The program also included the 2016 Society for Medicines Research Award Lecture given by Dr. Francis Cuss, Executive Vice President & CSO R& D, Bristol-Myers Squibb, on the discovery, development and delivery of Opdivo ( nivolumab), which is a fully human anti-programmed cell death protein 1 ( PD-1) antibody. The meeting was held at the National Heart and Lung Institute, Kensington, London, U. K. and was organized by the authors of this report.
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PD-1 inhibitor,Nivolumab,Opdivo,ATM kinase,AZD-0156,DNA-PK inhibitor,M-3814,Folate receptor alpha IgE antibody,MOv18,Respiratory syncytial virus fusion inhibitor,JNJ-53718678,KMO inhibitor,GSK-065,Sickle cell inhibitor,PF-04447943
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