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DISTURBED EXPRESSION OF IMMUNOREGULATORY LONG NONCODING RNAS IN CIRCULATING IMMUNE CELLS FROM PATIENTS WITH EARLY MYOCARDIAL INFARCTION

Wolfgang Poller,Martina Gast, Shinichi Nakagawa,Jan Haas,Andrea Stroux, Christian Mueller,Daniela Börnigen, Dirk Westermann,Carsten Skurk,Ursula Rauch-Kröhnert,Kannanganattu Prasanth,Stefan Blankenberg,Benjamin Meder,Ulf Landmesser, Tanja Zeller

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2017）

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Abstract
Background: Inflammation is a key driver of atherosclerosis and myocardial infarction (MI) and long noncoding RNAs (lncRNAs) are known to play a role in inflammatory processes. This study aimed to identify immunoregulatory lncRNAs, and to investigate their role in a translational approach from mouse
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Key words
noncoding rnas,circulating immune cells,myocardial infarction,immunoregulatory
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