Beta-Cryptoxanthin Exerts Better Cardioprotection Against Cardiac Ischemia-Reperfusion Injury Than Astaxanthin Via Protecting Mitochondrial Dysfunction In Mice

Wanpitak Pongkan,Liang Xu,Osamu Takatori,Naoto Nagata,Yinhua Ni, Mai Nakayama,Siriporn C. Chattipakorn,Soichiro Usui,Tsuguhito Ota,Nipon Chattipakorn

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2017）

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Abstract

Background: β-cryptoxanthin (BX) and astaxanthin (AX) are the antioxidant carotenoid pigments which inhibit lipid peroxidation as potently as vitamin E (Vit-E). Although high levels of these carotenoids and vitamin E have been linked to low risk of cardiovascular disease, their roles in cardiac

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Key words

mitochondrial dysfunction,astaxanthin,beta-cryptoxanthin,ischemia-reperfusion

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