Emergence and persistence of the Chikungunya virus East-Central-South-African genotype in Northeast Brazil

Antonio Charlys da Costa,Julien Thézé,Shirley Vasconcelos Komninakis,Rodrigo Lopes Sanz-Duro, Marta Rejane Lemos Felinto, Lucia Cristina Correa Moura,Ivoneide Moreira de Oliveira Barroso, Lucineide Eliziario Correia Santos,Mardjane Alves de Lemos Nunes,Adriana Avila Moura,José Lourenço,Xutao Deng,Eric Delwart,Maria Raquel dos Anjos Silva Guimarães,Oliver G. Pybus,Ester C. Sabino,Nuno Rodrigues Faria

bioRxiv（2017）

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摘要

We investigate an outbreak of exanthematous illness in Maceio, Alagoas, using molecular surveillance. Of 273 samples, 76% tested RT-qPCR positive for Chikungunya virus. Phylogenetic analysis reveals that the outbreak was caused by the East-Central-South-African genotype, and that this lineage has likely persisted since mid-2014 in Northeast Brazil.

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Chikungunya virus,Northeast region Brazil,genetic epidemiology

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