siRNA-nanoparticle conjugate in gene silencing: A future cure to deadly diseases?

Materials Science and Engineering: C(2017)

Cited 25|Views8
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Abstract
Alzheimers, cancer, acquired immune deficiency syndrome (AIDS) are considered to be some of the most deadly diseases of the 21st century on account of their severity and rapid increase in the number of affected population and with scarce cases of recovery, they still remain a troubling paradox. Specifically, with millions of cancer patients worldwide and lack of proper cure for the same, understanding the deadly disease at the molecular level and planning a therapeutic strategy in the same line is the need of the hour. Further, the potential threat of prevalence and escalation of Alzheimer's and HIV (human immunodeficiency virus) infection by more than three times as of recent past, needs a medical breakthrough to arrive at a meaningful solution to tackle the present day scenario.
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Key words
siRNA-nanoparticle conjugates,Gene silencing,Biocompatibility,Cancer,RNAi,Alzheimer's disease
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