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HCV resistance test guided retreatments after protease inhibitors failures can induce maximal efficacy rate in real-life

V. Cento,S. Barbaliscia,I. Lenci,T. Ruggiero,C. Masetti,Carlo Magni,Valeria Micheli,Stefania Paolucci,Y. Troshina,Elisa Biliotti,M. Milana,M. Melis,Elisabetta Teti,L. Lambiase,B. Menzaghi,L.A. Nicolini,Simona Marenco,V.C. Di Maio,M. Aragri,A. Pecchioli,A. Bertoli,F.P. Antonucci,Loredana Sarmati,C. Sarrecchia,Margherita Macera,Nicola Coppola,E. Danieli,Dante Romagnoli,A. Pellicelli,Stefano Bonora,Sergio Babudieri,A. Di Biagio,A. Picciotto,S. Novati,M. Siciliano,V. Messina,E. Claar,F. Baldanti,C. Pasquazzi,Alessia Ciancio,Massimo Puoti,Valeria Ghisetti,M. Andreoni,Gloria Taliani,Giuliano Rizzardini,M. Angelico,C.F. Perno,Francesca Ceccherini-Silberstein

DIGESTIVE AND LIVER DISEASE（2017）

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Abstract
Background and aims: We analyzed the efficacy of retreatment after protease inhibitors (PI) plus pegylated-interferon (pegIFN) and ribavirin (RBV)-failure with various IFN-free regimens, and the role of genotypic-resistance-testing (GRT) in real-life settings.
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Key words
protease inhibitors failures,resistance,maximal efficacy rate,real-life
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