Both R-loop removal and ribonucleotide excision repair activities of RNase H2 contribute substantially to chromosome stability

Deborah A. Cornelio,Hailey N.C. Sedam,Jessica A. Ferrarezi,Nadia M.V. Sampaio,Juan Lucas Argueso

DNA Repair（2017）

引用 27|浏览10

暂无评分

摘要

•Both enzymatic activities of RNase H2 contribute to chromosome stability.•Each activity makes a roughly equal contribution across a long chromosomal region.•The role of RER is dependent on Top1 and ribonucleotide incorporation by Pol ε.

查看译文

关键词

Ribonucleotides,R-loops,RNase H2,RNH201,Loss-of-heterozygosity (LOH)

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要