PDCT-09. HYPERMUTATION AND NEOANTIGEN FORMATION IS DIAGNOSTIC AND PREDICT RESPONSE TO IMMUNE CHECKPOINT INHIBITION IN CHILDHOOD BIALLELIC MISMATCH REPAIR DEFICIENT BRAIN TUMORS Brittany Campbell , Eric Bouffet , Valerie Larouche , Gary Mason , Alyssa T. Reddy , Michael Osborne , Vanan Magimairajan , Daniele Merico , Richard de Borja , Brian Hon-Yin Chung , Melissa Galati , Melyssa Aronson , Carol Durno , Joerg Krueger , Vanja Cabric , Nataliya Zhukova , Vijay Ramaswamy , Roula A. Farah , Samina Afzal , Michal Yalon , Gidi Rechavi , Michael D. Walsh , Dvir Rina , Elhasid Ronit , Michael Sullivan , Jordan R. Hansford , Andrew J. Dodgshun , Nancy Klauber-Demore , Lindsay L. Peterson , Sunil J. Patel , Scott M. Lindhorst , Jeffrey Atkinson , Rachel Laframboise , Zane Cohen , Peter Dirks , Michael Taylor , David Malkin , Steffen Albrecht , Roy Dudley , Nada Jabado , Cynthia Hawkins , Adam Shlien , Uri Tabori Neuro-oncology（2016）
关键词
immune checkpoint inhibition, brain tumors, neoantigen formation, hypermutation
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