The VKORC1 polymorphism rs9923231 is associated with aneurysms of the ascending aorta in an Austrian population

Martin Andreas,Adelheid Panzenboeck,Shiva Shabanian,Alfred Kocher,Christine Mannhalter, Adrian Petzl, Johanna Hueblauer,Michael Wolzt,Marek Ehrlich,Irene Lang

Thrombosis Research（2017）

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摘要

•The VKORC1: c.-1639 G>A polymorphism is associated with aneurysms of the ascending aorta.•Gamma-carboxylation may play a role in aneurysm development.•Protein levels of Matrix-Gla protein did not differ to control patients.

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