Headache Prevalence Following Recovery From Ttp And Ahus: A Single-Center, Cross Sectional Cohort Survey Study

Neurological injury is associated with an acute episode of microangiopathy, but only recently have persistent deficits in memory, concentration, mood and mental endurance been reported in patients who have long recovered from an acute episode of Thrombotic Thrombocytopenia Purpura (TTP). The mechanism for these findings remains unclear. To date, no studies have addressed the frequency or severity of headaches in patients with a previous history of TTP or atypical hemolytic uremic syndrome (aHUS). Based upon the longitudinal follow-up of our TTP and aHUS patients, we hypothesize that headaches are more incapacitating in patients with a history of TTP or aHUS than has been appreciated previously.