Optogenetic toolkit for precise control of calcium signaling

Guolin Ma,Shufan Wen,Lian He,Yun Huang,Youjun Wang,Yubin Zhou

Cell Calcium（2017）

引用 52|浏览9

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摘要

•Overview of genetically encoded Ca2+ actuators (GECAs) for control of calcium signaling.•Comparing engineering strategies and biophysical characteristics of GECAs.•Guidelines for selecting appropriate GECAs for context-dependent applications.

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关键词

Optogenetics,Calcium signaling,Genetically-encoded calcium actuator (GECA),LOV2,Cryptochrome,Calcium release-activated calcium (CRAC) channel

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