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Chondroitin sulfate immobilization at the surface of electrospun nanofiber meshes for cartilage tissue regeneration approaches

Juliana F. Piai,Marta Alves da Silva,Albino Martins,Ana Torres,Susana Faria,Rui L. Reis,Edvani C. Muniz,Nuno M. Neves

Applied Surface Science（2017）

Cited 35|Views6
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Abstract
•Chemical immobilization of chondroitin sulfate at the surface of nanofiber meshes.•CS-immobilized NFMs showed lower roughness and higher hydrophilicity.•CS-immobilized NFMs offer a highly effective substrate for hACs phenotypic stability.
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Key words
Chondroitin sulfate,Electrospun nanofiber meshes,Surface functionalization,Human articular condrocytes
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