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Cytosine DNA methylation at promoter of non LTR retrotransposon and heat shock protein gene (HSP70) of Entamoeba histolytica and lack of correlation with transcription status

Molecular and Biochemical Parasitology(2017)

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Abstract
•The retrotransposon EhLINE1 consists of transcriptionally active and silent copies.•The promoter of an active copy was located in a 841bp fragment at its 5′-end.•No cytosine methylation of promoter was seen in active or silent copies.•EhHsp70 promoter was fully methylated irrespective of transcription status.•Promoter methylation is not correlated with transcription level in E. histolytica.
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Key words
Non LTR retrotransposon EhLINE1,EhHsp70,Cytosine DNA methylation,Entamoeba histolytica,Transcriptional regulation,Bisulfite mapping
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