Development of approaches to fibrostatin F, N -acetyl- L -cysteinyl-containing 1,4-naphthoquinone metabolite of Streptomyces catenulae
RUSSIAN CHEMICAL BULLETIN(2016)
摘要
A possibility of the synthesis of microbial metabolite Streptomyces catenulae fibrostatin F through the AcOH-catalyzed condensation of 5-hydroxy-3-hydroxymethyl-2,7-dimethoxy1,4-naphthoquinone and its related 3-chloromethyl, 3-acetoxymethyl, and 3-methoxymethyl derivatives with N -acetyl-L-cysteine and paraformaldehyde in 1,4-dioxane was studied. In these conditions, all naphthoquinones gave N -acetyl- S -[(8-hydroxy-3,6-dimethoxy-1,4-dioxonaphthalen-2-yl)methyl]-L-cysteine isomeric to the natural fibrostatin C.
更多查看译文
关键词
fibrostatins,N-acetyl-L-cysteine,5-hydroxy-2,7-dimethoxy-3-methyl-1,4-naphthoquinones,N-acetyl-S-[(8-hydroxy-3,6-dimethoxy-1,4-dioxonaphthalen-2-yl) methyl]-L-cysteine,Streptomyces catenulae
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要