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Molecular similarity considerations in the licensing of orphan drugs

Pedro Franco,Nuria Porta,John D. Holliday,Peter Willett

Drug Discovery Today（2017）

Cited 8|Views1
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Abstract
•Authorisation and evaluation of orphan drugs.•Similarity in the in the context of the orphan drug legislation.•2D fingerprints used to evaluate similarity of orphan medicines.•Human assessment versus computer assessment.
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