Severe Anemia Early In Life As A Risk Factor For Sickle-Cell Kidney Disease

To the editor:Patients with sickle-cell disease (SCD) are at high risk for morbidity and mortality from SCD nephropathy.[1][1],[2][2] During adolescence, 20% to 35% of patients develop microalbuminuria (MiA; 30-300 mg/g Cr) classified as stage A2 chronic kidney disease (CKD) according to Kidney