NMR analysis of antitumor drugs: Doxorubicin, daunorubicin and their functionalized derivatives

Kinga Piorecka,Wlodzimierz A. Stanczyk,Marcin Florczak

Tetrahedron Letters（2017）

引用 21|浏览7

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摘要

•Synthesis of four novel anthracycline conjugates has been described.•Their structure has been determined via 1H and 13C NMR.•Corrected NMR data for doxorubicin and daunorubicin hydrochlorides are presented.•The novel modified anthracyclines allow conjugation with a variety of nanocarriers.

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关键词

NMR analysis,Anticancer drugs,Modification of anthracyclines,Doxorubicin and daunorubicin derivatives

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