Multiple beneficial effects of melanocortin MC4 receptor agonists in experimental neurodegenerative disorders: Therapeutic perspectives

Progress in Neurobiology(2017)

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摘要
•Melanocortins induce neuroprotection and neurogenesis in neurodegenerative disorders.•Melanocortins improve synaptic activity and neurological performance.•These effects are mediated by melanocortin MC4 receptors.
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关键词
,ACTH,AD,BDNF,BrdU,CNS,DG,ERK,HMGB-1,JNK,MSH,NDP-α-MSH,SAH,SCI,SGZ,Shh,IL,SVZ,TBI,TNF-α
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