274 Does Submucosal Injection Papillectomy Improve Procedure Outcomes Than Simple Snare Papillectomy

Injecting saline or diluted epinephrine solution into the submucosal layer of the gastrointestinal tract to lift the tumorous lesions is a common practice during endoscopic mucosal or submucosal resection. However, whether these solutions should also be used to lift the ampullary tumors during endoscopic snare papillectomy is not established, especially in view of achieving complete resection or preventing post-papillectomy bleeding. This study aimed to investigate the clinical efficacy of simple snaring papillectomy (SSP) versus submucosal injection papillectomy (SIP) in patients with ampulla of Vater adenoma.