Idiopathic Non-histaminergic Angioedema: Successful Treatment with Omalizumab in Five Patients

Journal of Clinical Immunology(2016)

引用 16|浏览7
暂无评分
摘要
Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease characterized by AE resistant to antihistamines and a chronic course. We report five new cases of InH-AAE (two women and three men) with a rapid and dramatic response to the anti-immunoglobulin-E antibody omalizumab. In our literature review, we found 13 other relevant cases with a good response to this treatment. Overall, in 6 out of 18 patients, the doses of omalizumab required to prevent recurrences of attacks were higher than the licensed dose for chronic urticaria. No significant adverse effects have been reported.
更多
查看译文
关键词
Idiopathic angioedema,non-histaminergic angioedema,omalizumab
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要