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Thermal, spectroscopic and biological studies on solid ibuprofen complexes of heavy trivalent lanthanides and yttrium

Bruno Barreto da Cunha Holanda,Renan Barrach Guerra,Alexandre de Oliveira Legendre, Débora de Fátima Almeida,Thais Fernanda de Campos Fraga-Silva,Ângela Carolina Finato,James Venturini,Gilbert Bannach

Thermochimica Acta（2017）

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Abstract
•Ibuprofen complexes of heavy trivalent lanthanides and yttrium have been synthetized.•The thermal analysis provided information about the thermal behavior of the samples.•Analysis of the IR spectra showed two coordination modes for compounds.•The TG-EGA-MIR showed propane as the gas evolved during the thermal decomposition.•Cytotoxicity and anti-inflammatory activity of the compounds were evaluated.
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Key words
Thermal behavior,Middle infrared spectroscopy,TG-EGA-MIR,Metallodrug,Lanthanides,Biological studies
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