A Case of Oropharyngeal Squamous Cell Carcinoma who Developed Sigmoid Colon Perforation after Cetuximab Treatment

A 73-year-old male was referred to our hospital complaining of swelling of his right neck, and was diagnosed as having oropharyngeal squamous cell carcinoma, clinical stage T2N2bM0. He had received concurrent radiotherapy with cetuximab treatment and achieved complete remission by the time he had received a total of 70 Gy of radiation to the neck and 7 courses of intravenous cetuximab treatment. However, he developed perforation of the sigmoid colon 1 month after completion of the cetuximab treatment.