Influence of intra-abdominal fat on surgical outcome and overall survival of patients with gastric cancer

Background: The aim of this study was to evaluate the impact of obesity on surgical outcome and prognosis in patients with gastric cancer. Methods: A total of 304 patients who underwent curative gastrectomy for gastric adenocarcinoma between January 2005 and March 2008were enrolled. Body mass index (BMI) was calculated before the operation and visceral fat area (VFA) was measured by abdominal computed tomography (CT). The patients were divided according to BMI class and VFA quartile. The influence of BMI and VFA on surgical outcome and survival was evaluated. Results: The median BMI was 23.3 kg/m 2 and the median VFA was 103 cm 2 . There was a significant positive correlation between BMI and VFA. According to BMI class and VFA quartile, there were no significant differences in patients’ characteristics or surgical outcome, with the exception of a significantly longer operation time and fewer retrieved lymph nodes in patients with a high BMI and VFA. The unadjusted overall and disease free survival were not significantly different between BMI classes or VFA