A direct synthesis of atractylodinol, a potent inhibitor of PRRSV, and its biological evaluation

George A. Kraus,Pengfei Dong,Yang Qu,Alyssa Evans,Susan Carpenter

Tetrahedron Letters（2016）

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摘要

•A synthesis of an inhibitor of the PRRS virus is described.•Analogs were evaluated for viral inhibition.•Analog 8 shows excellent inhibition of the PRRS virus.

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关键词

Total synthesis,Atractylodinol,PRRSV,Antiviral activity,In vitro

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