Synthesis of fluorinated oxazoles by oxidative cyclization of fluorinated enamides
Journal of Fluorine Chemistry(2017)
摘要
•Fluorinated isoxazoles were obtained by oxidation of the corresponding enamides.•These fluorinated building blocks are useful for Drug discovery and Agrochemistry.•Di- and trifluoromethyl-containing compounds were obtained.
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关键词
Acylation,Fluoroalkyl,Hypervalent iodine,Oxazole,Ring closure
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