Safety of the Northern Hemisphere 2014/2015 formulation of the inactivated split-virion intramuscular trivalent influenza vaccine

•Phase IV study on 2014/2015 Northern Hemisphere Vaxigrip.•Compared rates of solicited reactions in individuals ⩾6months with historical data.•No clinically significant increases in frequencies of solicited reactions.•No specific concerns identified for the 2014/2015 Northern Hemisphere formulation.•The 2014/2015 Northern Hemisphere formulation of Vaxigrip meets EU requirements.