Normal Hematologic Parameters And Fetal Hemoglobin Silencing With Heterozygous Ikzf1 Mutations

Nour Abdulhay,Claudia Fiorini,Attila Kumanovics, Ashleigh A. Sun, Jeannette Hansen-Rejali,Karl V. Voelkerding,Sergio D. Rosenzweig,Harry R. Hill,Vijay G. Sankaran

BLOOD（2016）

Cited 7|Views33

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Abstract

To the editor:The multiple zinc finger-containing transcription factor, IKAROS/IKZF1, has multifaceted roles in hematopoiesis.[1][1] Numerous studies using both human primary hematopoietic cells and mouse models have suggested that IKZF1 plays a key role in erythropoiesis and the fetal-to-adult

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