Final Results From A Phase 4 Open-Label 3-Year Study Evaluating Changes In Bone Marrow (Bm) Morphology In Adult Immune Thrombocytopenia (Itp) Patients (Pts) Receiving The Thrombopoietin Mimetic Romiplostim

Introduction: Normal bm may contain reticulin, which is of unknown clinical relevance. An analysis of romiplostim ITP trials as of 2011 showed 17 reticulin cases and one collagen case; however, biopsies were not performed systematically. Reported here are final results from a prospective 3-year (y) study evaluating bm biopsies for reticulin and collagen before and after treatment with romiplostim in adult ITP pts.