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The Relationship Between Metformin and Serum Prostate‐Specific Antigen Levels

Viranda H. Jayalath,Christopher Ireland,Neil E. Fleshner,Robert J. Hamilton,David J. A. Jenkins

The Prostate（2016）

Cited 20|Views12
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Abstract
Metformin is the first‐line oral antihyperglycemic of choice for individuals with type 2 diabetes. Recent evidence supports a role for metformin in prostate cancer chemoprotection. However, whether metformin indeed influences prostate biology is unknown. We aimed to study the association between metformin and serum prostate‐specific antigen (PSA) levels—the primary prostate cancer biomarker.
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Key words
metformin,prostate cancer,PSA,antihyperglycemic,cross-sectional,dose-response
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