Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells

Renyu Lin,Ziheng Zhang,Lingfeng Chen,Yunfang Zhou,Peng Zou,Chen Feng,Li Wang,Guang Liang

Cancer Letters（2016）

Cited 214|Views9

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Abstract

•Dihydroartemisinin (DHA) induces ferroptosis in head and neck carcinoma cells.•FOXM1 is implicated in DHA-mediated cell cycle arrest.•DHA holds promise as a treatment strategy for head and neck cancer.

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Key words

Head and neck cancer,Dihydroartemisinin,Ferroptosis,Antitumor,Cell cycle

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