Genetically Different Highly Pathogenic Avian Influenza A(H5N1) Viruses in West Africa, 2015.

Luca Tassoni,Alice Fusaro,Adelaide Milani,Philippe Lemey,Joseph A. Awuni, Victoria Bernice Sedor, Otilia Dogbey,Abraham Nii Okai Commey,Clement Meseko,Tony Joannis,Germaine Minoungou, Lassina Ouattara, Abdoul Malick Haido, Diarra Cisse-Aman,Emmanuel Couacy-Hymann,Gwenaelle Dauphin,Isabella Monne

EMERGING INFECTIOUS DISEASES（2016）

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摘要

To trace the evolution of highly pathogenic influenza A(H5N1) virus in West Africa, we sequenced genomes of 43 viruses collected during 2015 from poultry and wild birds in 5 countries. We found 2 co-circulating genetic groups within Glade 2.3.2.1c. Mutations that may increase adaptation to mammals raise concern over possible risk for humans.

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Africa,H5N1 subtype,HPAI,Influenza A virus,West Africa,genetic groups,highly pathogenic avian influenza,phylogeny,respiratory infections,viruses

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