Letter by Du et al Regarding Article, "Neutrophil-to-Lymphocyte Ratio Predicts the Outcome of Acute Intracerebral Hemorrhage".

With great interest and appreciation, we have read the article by Lattanzi et al1 The study revealed higher neutrophils, lower lymphocytes, and a higher neutrophil:lymphocyte ratio (NLR) predicted worse 3-month outcome after intracerebral hemorrhage (ICH) and could aid in the risk stratification of patients with acute ICH. However, results from the study should be interpreted with the following considerations.First, this is a retrospective cohort study conducted in a single hospital with limited sample size that has relatively low statistical powers. Some other diseases, such as neoplasm, autoimmune disease, infectious disease, systemic inflammatory disease, or surgery having an effect on NLRs were not excluded in this study. The general limitation of …