Primary spinal glioblastoma multiforme presenting with leptomeningeal gliomatosis and subarachnoid hemorrhage: A case report

•We present a rare case of spinal GBM with leptomeningeal gliomatosis at the time of diagnosis involving the Brainstem presenting clinically with typical subarachnoid hemorrhage in a 39-year-old female.•At the admission, cerebral angiography, CT scan and MRI of the brain showed no abnormality except for not requiring therapy Isolate small developmental venous anomaly (DVA li.-frontal).•Due to worsen of the headache, a new MRI 3-Tesla scan of the brain and total neural axis has been performed, which demonstrated an unclear lesion intraspinal intradural with contrast enhancement in the level C4/5 ventro-lateral, T2/3 dorso-lateral, L1/2 and L3 with diffuse leptomeningeal contrast until brainstem (pons).•An open Biopsy was done after laminectomy T2.•The clinical situation had been dramatic worsened with blindness and paralysis in upper limb both side.