Microbiota-sensitive drug delivery systems based on natural polysaccharides for colon targeting
Drug Discovery Today(2023)
Abstract
•Overview of colonic drug delivery systems.•Potential for local and systemic delivery.•Key focus on metabolic activity of the colonic microbiota.•Challenges of microbiota-sensitive natural polysaccharides.•Laying special emphasize on oral dosage forms of chemical and biological drugs.
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