Therapeutic Effects Of Labisia Pumila On Estrogen-Deficiency Related Disorders: An Evidence Based Review

This study explores the therapeutic effects of Labisia pumila (LP) in protection against estrogen-deficiency disorders. A systemic review of the literatures was conducted to identify the relevant studies on LP. A comprehensive search was conducted in Medline via Ebscohost and Scopus for relevant studies published between the years of 1946-2014. The main inclusion criteria were research articles published in english, studies had to report the association or the therapeutic effects of LP in various pathological conditions which are related to lifestyle variables, aging or experimentally-induced conditions. The literature search identified 97 potentially relevant articles, whereby 11 met the inclusion criteria. Altogether, there were nine animal studies and two human studies included in this study. There were eleven articles on protection against estrogen-deficiency disorders. In conclusion, LP may be used as an alternative treatment of estrogen deficiency orpost-menopausal-related diseases.