Cd30-Targeting Drugs: Cure For Mastocytosis?

BLOOD(2015)

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摘要
New promising targets and targeted drugs for treatment of aggressive forms of systemic mastocytosis are few; in this issue of Blood, Blatt et al(1) provide evidence that aberrant Ki-1 antigen (CD30) expression on neoplastic mast cells may serve as a therapeutic target of brentuximab-vedotin alone or in combination with KIT-targeting drugs.
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