Molecular Profiling by Next-Generation Sequencing in Nonsmall Cell Lung Cancer

Weiqiang Zhao,Susan Long, Greg Burton,Kara Patterson,Nehad Mohamed,Miguel Villalona,Gregory A. Otterson,Sameek Roychowdhury,Konstantin Shilo, Amy Gewirtz

AMERICAN JOURNAL OF CLINICAL PATHOLOGY（2013）

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摘要

Recent technology advances in multiplex genotyping and high-throughput genomic profiling by next-generation sequencing (NGS) technologies now offer the possibility of rapidly and comprehensively interrogating the cancer genome of individual patients from small tumor biopsies but sufficient data to support the clinical utilization are limited. Surgically resected formalin-fixed paraffin-embedded (FFPE) tumor tissues from 26 consecutive patients with NSCLC with known …

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molecular profiling,cancer,lung,next-generation

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