Genetic evidence for involvement of membrane trafficking in the action of 5-fluorouracil

Lingling Hu,Fan Yao,Yan Ma,Qiannan Liu,Si Chen,Tsutomu Hayafuji,Takayoshi Kuno,Yue Fang

Fungal Genetics and Biology（2016）

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摘要

•50 hypersensitive and 12 resistant mutants to 5-FU were identified.•The second largest functional group of the genes identified is implicated in membrane trafficking.•5-FU affects membrane trafficking in fission yeast.

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关键词

5-FU,5-FC,YPD,EMM,YES,GFP,TS

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