The frontier of RNA metamorphosis and ribosome signature in neocortical development
International Journal of Developmental Neuroscience(2016)
Abstract
•mRNA translation (protein synthesis) by the ribosome is a rapidly tunable and dynamic molecular mechanism in the developing nervous system.•Ribosomes have differential protein compositions based on localization, developmental-stage, and cell-type specificity.•Timed extracellular signals regulate ribosomal complexes and mRNA translation specificity.
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