A risk factor relativity study between Apelin levels of plasma adipokines and type 2 diabetes complicated with heart disease

Objective To investigate the relativity between Apelin levels of plasma adipokines and type 2 diabetes complicated with heart disease. Methods Fifty cases of type 2 diabetic patients with coronary heart disease were selected as observation group,and other 50 cases of type 2 diabetic patients without coronary heart disease in same period were selected as control group. The plasma Apelin levels of two groups were compared. The relativity between Apelin levels of plasma adipokines and the risk factors of type 2 diabetes with heart disease were analyzed by multiple factor Logistic regression. Results Plasma Apelin levels of patients in the observation group were( 2. 37 ± 0. 62) ng / ml,which were lower than that of the control group( P 0. 01). Multiple factor Logistic regression analysis results showed that low plasma Apelin levels were an independent risk factor for coronary heart disease in diabetic patients( OR: 0. 693,95% CI: 0. 427 ~ 0. 872,P 0. 01). Conclusion Plasma Apelin levels of type 2 diabetic patients with coronary heart disease were significantly lower than that of patients without coronary heart disease,which show that plasma Apelin levels can be used to predict the risk of type 2 diabetes complicated with coronary heart disease.