Effect of Shenkang Injection and Yiqi Qianshi Mixture for Chronic Glomerulonephritis with Qi Deficiency and Blood Stasis

Objective:To explore the clinical efficacy of Shenkang injection and Yiqi Qianshi mixture for the treatment of chronic glomerulonephritis. Methods:Sixty patients of chronic glomerulonephritis with qi deficiency and blood stasis were divided into control group and observation group,30 cases in each group. Both groups received conventional treatment and Shenkang injection intravenously,and the observation group was given Yiqi Qianshi mixture additionally. The treatment lasted for three months,and the follow up covered six months. Clinical effect and related indexes of renal function were observed. Results:The total effective rate was 93.3% in the observation group,and was 70.0% in the control group,the difference being significant(P 0.05). After treatment,24-hour urinary protein,serum creatinine(SCr),blood urea nitrogen(BUN) were deceased significantly in both groups(P 0.05 compared with those before treatment). The improvement of 24-hour urine protein,SCr,BUN in the observation group was superior to that in the control group(P 0.05). Conclusion:Shenkang injection and Yiqi Qianshi mixture can improve renal function of patients with chronic glomerulonephritis,and delay the progression of chronic glomerulonephritis.