Haemolysis assessment of Comfort denture adhesive

Objective To evaluate the haemolysis effect of synthetic macromolecular resin class of denture adhesive, which was developed by the authors. Methods This study was carried out in three groups:①experimental group application with Comfort DA; ②negative group application with normal saline; ③positive group application with distilled water. Each group was tested in triplicate. 0.1 ml diluted rabbit blood with anticoagulant was added to each tested tube. Absorbance of all the tested tubes was measured by a spectrophotometer at 545 nm after 90 min. Results Haemolysis rate of sample of Comfort DA was 2.95 %. Conclusion The developed Comfort denture adhesive didn't exhibit haemolysis effect.