可吸收性医用珊瑚人工骨的致突变性研究
Jilin Medical Journal(2004)
Abstract
目的:评价珊瑚人工骨的遗传毒性.方法:采用Ames试验;细胞染色体畸变试验和小鼠骨髓细胞微核试验.结果:不同浓度的浸提液加与不加S9mix条件下Ames试验;细胞染色体畸变试验以及微核试验与阴性对照组比较无显著差异,结果为阴性.结论:在本试验系统条件下,可吸收性珊瑚人工骨无致突变作用.
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