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Advances in Research in Connection Between Neutrophil and Myocardial Reperfusion after Acute Myocardial Infarction

Advances in Cardiovascular Diseases(2013)

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Abstract
Suboptimal myocardial reperfusion after reperfusion therapy in acute myocardial infarction( AMI) was associated with poor prognosis.Neutrophil activation,congregation,the formation of platelet-leukocyte complexes and oxidative stress play a key role in impaired myocardial perfusion in AMI.Inflammation may be a common link between epicardial macrovascular and impaired myocardial perfusion.Inhibition neutrophil activation,congregation,the formation of platelet-leukocyte complexes may improve myocardial reperfusion and prognosis in AMI.
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Key words
Reperfusion Therapy,Cardioprotection,Ischemic Preconditioning,Myocardial Infarction,Microcirculation
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