危重病患者SIRS期细胞因子水平与APACHE Ⅱ评分相关性研究
Tianjing Medical Journal（2002）
Abstract
目的:研究危重病患者SIRS期肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL1β)和白细胞介素-6(IL6)的水平与APACHE Ⅱ评分的相关性,并探讨其临床意义.方法:采用ELISA法检测30例危重病患者SIRS期TNF-α、IL1β、IL-6水平,并进行APACHE Ⅱ评分.结果:30例患者血中TNF-α、IL-1β、IL6水平均高于正常对照组(P＜0.01),与APACHE Ⅱ评分呈正相关(P＜0.05).结论:同步检测细胞因子活性及进行APACHE Ⅱ评分有助于危重病病情评估及预后判断.
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Key words
Inflammation
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