防治急性胰腺炎并发肝脏损害的实验研究

Chinese Journal of Bases and Clinics in General Surgery(2004)

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Abstract
目的 探讨急性胰腺炎(AP)时大鼠肝脏损害及中药七叶皂苷钠对该损害的影响.方法将大鼠分成3组,对照组、AP组和七叶皂苷钠治疗组(简称治疗组).通过对AP大鼠静脉注射七叶皂苷钠,测定各组肝组织内能荷及ATP的含量、血清乳酸脱氢酶、谷丙转氨酶和血清蛋白含量等各项指标,并观察胰腺和肝组织的病理变化.结果治疗组较AP组肝组织内细胞能荷及ATP的含量高,肝功能损害轻.结论 AP时常伴肝脏功能受损,应用七叶皂苷钠静脉注射,可以减轻AP大鼠肝脏损害.
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Key words
pancreatitis,aescin,rat liver
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