Prognostic Factors of 135 Nasopharyngeal Carcinoma Patients Treated With Radiotherapy

Objective To analyze the prognostic factors of nasopharyngeal carcinoma treated with radiotherapy.Methods 135 preliminary diagnosed patients were selected and treated with radiotherapy to a total dose of 68～80 Gy in 7～8 weeks. In order to analyze the factors affecting prognosis of NPC,SPSS analysis and Cox regression analysis were used to identify the prognostic factors.Results The overall 10-year survival rate was 48 9%; Univariate analysis suggested that 8 out of 13 items were significant factors for prognosis (P0 05). Multiple factors analysis suggested that only cranial nerve palsy ,skull base invasion and N stage were significant factors for prognosis.Conclusions Prognosis of patients with cranial nerve palsy and/or skull base invasion and /or bigger cervical tumor is poor.Comprehensive treatment may reduce relapse and metastasis and improve the patient's survival.