Ca~(2+)-independent Phosphorylation of Myosin on Smooth Muscle Myosin by Myosin Light Chain Kinase
Science Technology and Engineering(2002)
摘要
The characterization of Ca~(2+)-independent phosphorylation of myosin by MLCK was investigated.The results indicated that MLCK phosphorylated myosin not only in the Ca~(2+)-dependent way,but also in a Ca~(2+)-independent way.By using MLCK,the Ca~(2+)-independent phosphorylation of myosin needed much higher concentration of MLCK,and was less influenced by increasing the incubation temperature,prolonging incubation time,and increasing the K~+-ion strength compared to the Ca~(2+)-dependcnt phosphorylation.The results suggest that the Ca~(2+)-independent phosphorylation of myosin by MLCK be a new mechanism and involve in maintaining the tension of smooth muscle.
更多查看译文
关键词
myosin light chain kinase,smooth muscle myosin,phosphorylation
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要