Coordinating properties of peptides containing histidyl residues

Imre Sóvágó,Katalin Várnagy,Norbert Lihi,Ágnes Grenács

Coordination Chemistry Reviews（2016）

Cited 80|Views4

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Abstract

•Imidazole nitrogens are the primary ligating sites of peptides containing histidyl residues.•Formation of macrochelates is preferred for multihistidine peptides.•Internal histidines can be effective anchors for amide binding.•Multihistidine peptides can bind as many copper(II) ions as the number of histidyl sites.

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Key words

Copper(II),Nickel(II),Zinc(II),Histidine,Peptide,Structure

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