Elevated Creatinine Kinase in Connection with Wilson Disease: Atypical Presentation with Musculoskeletal Symptoms or Associated Neuromuscular Disease

Background: Combination of an elevated creatinine kinase (ck) with transaminase elevation guide primarily to assumed diagnosis of neuromuscular disease. In rare cases an elevated ck with musculoskeletal symptoms can be the initial manifestation of Wilson disease. An early diagnosis of Wilson disease is important to avoid a toxical concretion of copper in the tissue.